Implantation rate in relation to age
The implantation rate is the chance of an individual embryo to implant, as defined by the number of gestational sacs per 100 embryo's transferred. Obviously this is different from the chance of a pregnancy per embryo transfer (ET) as one usually transfers more than one embryo per ET.
Fig:
CLINICAL IMPLANTATION RATE AND AGE
Fig: Implantation rate in relation to age in 7243 embryos transferred between 1989 and 1993 in the Diaconessenhuis Voorburg, analysed with weighed regression analysis. The light blue stars depict the real percentages per year, the yellow lines show the 5th, 50th and 95th percentile of a weighed regression analysis of this group.
It is clear that there is a strong correlation with age: The chance of implantation for a woman of 27 y per embryo transfererred is double that of a woman of 40 y, and about five times as large as that of a woman of 43 y. On top of this will come the miscarriage rate, which is also dependent on age. We will show this on a separate page.
A weighed regression analysis is performed as the number of embryos in each group are not the same: in some years there are many embryo's, in other years there are less. The number of embryo's in any particular year determines the weight-factor. (Analysis Joanneke in 't Hout, statistician)