Introduction

Transfer of blastocysts may be a promising new technique for certain patients in which it is difficult to make the selection of the best embryo purely based on the morphology on day two or day three after IVF or ICSI. At this moment the embryos are still largely dependent on the maternal genome, and the full transition to the embryonic genome has only taken place after the 8 cell stage. Therefore when genetic damage exists on the embryonic genome this sometimes may only become evident at or after the morula stage.

As we have shown that the morphology of day 3 embryos for blastocyst formation is limited some patients may benefit from postponing the transfer provided the culture conditions are optimal to sustain embryonic growth at that stage. (text abstract)

However it will be self-evident that follow-up of pregnancies obtained after transfer of blastocysts is imperative. We therefore call upon all centers that perform transfer of blastocysts to participate in the registry

To gain access to the Blastocyst multicenter registration site you need to get an access code. You can request an access code in by filling in the registration form, that you can obtain by clicking on the hyperlink. Please copy the data from the registration form at the left button to a Word or WP file, and mail it to me, or Fax it to +31.70.3401173. Once you have an access code you also can enter directly by www.blastocyst.net or you can enter via the ESHRE site (European Society for Human Reproduction and Embryology)

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Disclaimer:This information is not intended as a substitute for medical advice of physicians. The reader should regularly consult a physician in matters relating to his or her health and particularly with respect to any symptoms that may require diagnosis or medical attention.

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